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State-of-the-Art Strategies for the Prevention of Ischemic Disease on Both...

Rajeev Gupta and David Wood's important recent article in Lancet, "Primary Prevention of Ischemic heart disease: populations, individuals, and health professionals" opens by defining primordial...

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Should the 10-Year Results From the SYNTAX Trial Redefine Who We Consider for...

During the European Society of Cardiology Congress 2019 (ESC Congress 2019), one of the highly anticipated late-breaking clinical trials was SYNTAXES (SYNTAX Extended Survival Study), the 10-year...

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Secondary Prevention After CABG and Long-Term Mortality: Perspectives From...

Coronary artery bypass grafting (CABG) is the most commonly performed cardiac surgical procedure, with approximately 400,000 procedures performed in the United States annually, and the preferred method...

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Prognostic Implications of Moderate AS: Insights from the National...

Aortic stenosis (AS) is the most common valvular disorder in Europe and North America. The risk for mortality in patients with severe symptomatic AS has been clearly established, but the morbidity and...

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A Tale of Two Studies: Are We Closing in on Rational Therapy for Secondary MR?

The 2-year follow-up data from the MITRA-FR (Percutaneous Repair With the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation) trial was presented at the European Society of...

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Major Clinical Trials From ESC Congress 2019: Surgeons' Perspectives

The European Society of Cardiology Congress 2019 (ESC Congress 2019) provided many important randomized trials in the field of cardiovascular medicine.

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Doubt for Vitamin D in Diabetes Prevention

Diabetes mellitus is a major public health problem, with 1.5 million new cases of diabetes diagnosed each year in the United States alone.

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Inclisiran for Heterozygous Familial Hypercholesterolemia

The goal of the ORION-9 trial was to assess the safety and efficacy of inclisiran in lowering low-density lipoprotein cholesterol (LDL-C) among patients with heterozygous familial hypercholesterolemia...

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Understanding the Effects of Genetic Exposure to Low LDL-C and Systolic Blood...

For several decades, efforts in Preventive Cardiology have focused on early risk detection and treating high risk patients with lipid and blood pressure lowering therapies as well as trying to optimize...

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Weight Variability and Cardiovascular Outcomes in Patients with Type 2...

Obesity is an important driving factor for the development of type 2 diabetes mellitus (T2DM). Further, the majority of individuals with T2DM are overweight. Both obesity and diabetes predispose to...

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Obesity-Mediated AF and Sodium Channel Blocker Antiarrhythmics

Does obesity differentially mediate response to antiarrhythmic drugs (AADs) in patients with symptomatic atrial fibrillation (AF) and in mice with diet-induced obesity (DIO) and pacing-induced AF?

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Exercise Before, During, and After Cancer Therapy

Early detection of cancer and its effective management have considerably improved the 5-year disease-survival rates of common malignancies.

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Leg Pain During Exercise or Driving

A 26-year old male, who is a long-distance runner, presents to his doctor complaining of right foot pain during aerobic exercise in the last two months. He says that the pain exacerbates with training...

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Clinical Review on Triglycerides

The following are key points to remember from this clinical review on triglycerides.

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Summary Slide | ORION-9

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Feature | Newer Drugs, Better Outcomes in Heart Failure: A Look at Results at...

At AHA 2019, more results from the DAPA-HF and EMPA-REG Outcomes trials with SGLT2 inhibitors help refine our understanding of the benefit of these drugs in patients with and without diabetes.

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Dietary Cholesterol and Cardiovascular Risk: AHA Advisory

The following are key points to remember from the American Heart Association (AHA) Advisory on dietary cholesterol and cardiovascular risk.

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Assessing Need for Statin Therapy in Older Adults

AJ is a 78-year-old African American female with hypertension, prediabetes, and chronic kidney disease who presents to the primary care physician's (PCP) clinic for her annual wellness visit.

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Expert Opinion: Fat for Thought – Any Role for the Ketogenic Diet in...

For at least the last century, nearly every track and field coach in America has ended practice the day before a big meet with the same advice: "make sure you carbo-load tonight!"

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Expert Opinion: "Crazy for Ketones"– The Ketogenic Diet in Athletes:...

Athletic performance and physique have been closely associated with diet and nutrition for ages.

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